Wikipedia: Long was born in Danielsville, Madison County, Georgia. He received his M.D. degree at the University of Pennsylvania in 1839. After observing the same physiological effects with diethyl ether ("ether") that Humphry Davy had described for nitrous oxide in 1800, Long used ether for the first time on March 30, 1842 to remove a tumor from the neck of a patient, James M. Venable, in Jefferson, Georgia. Long subsequently removed a second tumor from Venable and used ether as an anesthetic in amputations and childbirth. The results of these trials were published in 1848 in The Southern Medical and Surgical Journal. An original copy of this publication is held in the U.S. National Library of Medicine.
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