The common phenotypic features of Branchio-Oto-Renal Syndrome are hearing loss (incidence 93%), preauricular pits or tags (82%), renal anomalies (67%), branchial fistulae (49%), pinnae deformity (36%) and external auditory canal stenosis (29%). The severity of hearing loss ranges from mild to profound and can be conductive, sensorineural and mixed. In addition to external auditory canal stenosis atresia occurs. Middle ear anomalies can include malformation, malposition, dislocation or fixation of the ossicles, and reduction in size or malformation of the middle ear cavity. Inner ear malformations include cochlear hypoplasia, enlargement of the cochlear and vestibular aqueducts, and hypoplasia of the lateral semicircular canal.(Chen, Francis et al. 1995). Renal anomalies range from hypoplasia to aplasia, either unilaterally or bilaterally. Anomalies of the collecting system affect the ureter, calyx and renal pelvis. (Fraser, Ayme et al. 1983; Heimler and Lieber 1986; Konig, Fuchs et al. 1994).
(Based on a page at the University of Iowa.)
Please submit sites that pertain to end stage disease to this area.End-stage kidney disease is a complete or near complete failure of the kidneys to function to excrete wastes, concentrate urine, and regulate electrolytes. Also called End-stage renal disease (ESRD).
Sites selling products will not be listed here.
Submit sites about Glomerulonephritis to this area.Glomerulonephritis is a type of kidney disease caused by inflammation of the internal kidney structures (glomeruli).
Sites must be in English. Non-English sites should be submitted to a proper World category instead.
Please submit only sites about Minimal Change Glomerulopathy to this area.A disorder of the kidneys that affects the structures (glomeruli) which include small capillaries surrounded by membranes through which the blood is filtered to form urine.
Sites selling products should be submitted to a Shopping category.
Sites listed here will represent official organizations involved with the topic of kidney disease.There is currently no description created for this category.
Patient support groups and networks are listed under Support Groups.
Sites listed here will represent projects, departments, and other groups undertaking research into kidney disease. Sites with a focus on raising money for research do not belong here unless they are involved in the research itself.There is currently no description created for this category.
Please submit only sites that are about kidney stones to this area.Urinary Calculus: stone formed in any part of the urinary system (kidney, ureter, bladder); some are small enough to pass in the urine, with or without pain; others must be removed surgically.
Sites selling supplements and products should be submitted to a Shopping category instead.
If the site you wish to submit does not have a version in English please look for an appropriate category in World.
Sites listed here will represent support networks with a physical address and/or a web presence. Those with a physical address may also be submitted to the relevant Regional subcategory.There is currently no description created for this category.