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Gangrene is a localised area of tissue death and is normally the result of a critically insufficient blood supply to part of the body. It can be classified as dry or wet.
Dry gangrene does not cause sepsis or cause the patient to die. However, it can result in local tissue death with the tissue eventually being sloughed off.
Wet gangrene is usually infected by bacteria, and if left untreated, the patient usually develops sepsis and dies within a few hours or days.