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• Article on RNAi by GNN - Online article describing gene silencing mechanism and how RNAi can be used for HIV treatment.
• Article on RNAi by HOPES - Online article describes basic mechanism of RNAi and how it can be applied for Huntington's disease treatment.
• Article on siRNA from Wikipedia - Describes small interfering RNA (siRNA) function, structure, use in research, and potential application for therapy.
• Cambridge Healthtech Institute - CHI organizes RNAi-related conferences throughout the US and Europe, including therapeutics, pharmaceutics, drug development, target discovery, and biodefense. Provides biotechnology news and conferences information.
• CnidBase: Cnidarian Evolutionary Genomics Database - Cnidbase provides tools for researchers interested in studying gene expression of these organisms. Provides sequence BLAST tools, keyword search of genes and homologs, a literature scan, and several useful links.
• DBTGR - Database of Tunicate Gene Regulation - Gene expression database of tunicates. Provides the descriptions of 12 transcription factors and 140 promoters.
• Discovery on Target RNAi meeting - Annual RNAi meeting hosted by Cambridge Healthcare Institute in Boston, Massachusetts. Meeting provides overview of various aspects in RNA Interference (RNAi) research, ranging from in vitro and in vivo drug discovery research to therapeutic applications. Online meeting information is available: plenary sessions, exhibits, and poster presentations.
• Drosophila RNAi Resource - Informational RNAi resource on studying drosophila genes and their roles in development by Society for Developmental Biology.
• Gene Silencing Mechanism - Animation of post transcriptional gene silencing or RNA Interference (RNAi) by Nature Reviews Genetics.
• Genetic Diversity - Provides educational modules covering such parts of biology as genetics, cell biology, and gene expression.
• Journal of RNAi and Gene Silencing - Publishes peer-reviewed articles addressing the biology and application of RNA interference and gene silencing. Includes information about journal aims and scope, publication policies, and manuscript submission. Provides online access to journal articles.
• microRNA and Cancer Therapeutics - Online review of microRNA application for potential therapy of cancer by Dmitriy Ovcharenko.
• The microRNA Registry - Online resource provides a service for the assignment of miRNA gene names. Provides searchable database of published miRNA sequences. Includes data and research application information.
• miRNAMap - Collection of published miRNAs from the microRNA registry and predict putative miRNA precursors based on genome-wide mapping of conserved RNA secondary structures.
• The MIT/ICBP siRNA Database - Online resource for researchers looking for experimentally validated siRNAs and shRNAs against target genes, with a focus on genes thought to be involved in cancer.
• NANOPOLIS - Educational portal providing nanotechnology articles and multimedia courses in the multidisciplinary research areas.
• Nature web focus: RNAi - Online review of RNA Interference biological phenomena. Includes citations of recent research publications, RNAi animations, and science news articles.
• Navigating Journey of Genome to Medicine - Review article on RNAi by International Herald Tribune. Provides an overview on RNA Interference discovery, current research efforts, and therapeutic potential.
• Nuclear Receptor Signaling Atlas - Informational portal for researchers interested in nuclear receptor signaling.
• Oligoengine - Oligonucleotide design software for applications such as RNAi, DNA methylation, antisense, and genome arrays.
• Oligonucleotide Therapeutic Society - Society host conferences on academia and industry-based research and development of oligonucleotide therapeutics: RNAi, antisense, and others. Provides society overview, publication materials, meetings, and contact information.
• Ordway Research Institute - Not-for-profit corporation with a mission to translate basic science observations into therapeutics. Provides research services including quantitation of endogenous levels of microRNAs and mRNAs from experimental samples. Includes information on research focus areas and technology development.
• RNA Interference - Interactive online resource from Howard Hughes Medical Institute. Presents RNAi mechanism and overview of key scientific findings.
• RNA Interference at Journal Nature - Focus RNA Interference - online resource publishing recent advances in RNAi field, and novel applications in Nature Cell Biology and Nature Reviews.
• The RNAi Cure - A NOVA ScienceNOW science program by PBS feature the possible applications for RNAi therapy. Provides animations of key biological processes and mechanism of RNA Interference.
• RNAi Database - Includes all siRNA from C. elegans including assay, resulting phenotypes, dsRNA target location. Database provides Gene/Protein or Phenotype search options.
• RNAi Database - Provides access to results from RNAi interference studies in C. elegans. Includes images, movies, phenotypes, and graphical maps. Many of the entries in the database are for ovary-expressed or germline-enriched genes.
• RNAi Gateway - Web resource from BioMed Central. Provides RNA Interference (RNAi) research highlights, journal links, news, and meeting information.
• RNAi Mechanism Animation by Journal Nature - An animation from Nature Publishing Group on the mechanism of RNA Interference (RNAi).
• RNAi News - Online resource for scientists, researchers, technologists, and executives engaged in RNA Interference, functional genomics, and drug discovery. Offers industry news, product reviews, and meetings information.
• RNAi Resource at Ambion - Online RNA Interference (RNAi) resource. Provide scientific and technical support, information on microRNA and small interfering RNA application in gene expression research.
• RNAi Resource at Macalester College - Informational resource, including RNAi mechanism, overview of current studies, and related research protocols.
• RNAi Transfection Forum - Biotechnology research forum discussing RNAi, RT-PCR, DNA and siRNA transfection, cloning, stable cells, protein expression in vitro, in vivo siRNA delivery, and other molecular biology RNAi methods and transfection protocols.
• RNAi Transfection Resource - Review of transfection techniques such as electroporation, denrimers and lipids that are used for transfection of DNA, RNA, and siRNA. Includes information on optimized cell type specific transfection systems.
• The RNAi vs. HIV - Reviews the use of this therapy in fighting HIV. Includes mechanism, difficulties, terms, and featured experiments.
• The RNAi Web - Online resource for RNA Interference (RNAi) technology. Offers overview of technology, references, and links on other RNAi-related web resources.
• RNAi@elegansNet - Directory on gene silencing by RNA interference (RNAi) literature and resources.
• RNAi.net - Online resource offering information RNA interference and related issues: news, interviews, articles, techniques.
• Rosetta Genomics - Israel-based microRNA genomics company, develops bioinformatic tools for miRNA gene detection approach.
• Second Annual Meeting of the Oligonucleotide Therapeutics Society - Yearly conference organized by New York Academy of Sciences. Scientists from industry and academia meet to discuss use of oligonucleotide-based gene-silencing techniques for development of innovative therapeutics. Includes information about conference registration, preliminary program, and abstract submission.
• SI RNA - Small Interference RNA Resources - Online resource from Ion Channel Media Group. Provides news, publication links, and citations of the recent literature relevant to RNA Interference research.
• Silencing Genomes - Portal about genome-wide applications of RNAi by Cold Spring Harbor Laboratory.
• siRNA Transfection Resource - Cell biology educational resource focused on RNAi and siRNA transfection process. Describes siRNA biological mechanism of action, high-throughput RNAi screens, stable shRNA expression, experimental transfection protocols, and in vivo siRNA applications.
• The siRNA User Guide - Online guide for performing RNAi experiments using synthetic siRNA molecules. By Tuschl Lab at Rockefeller University.
• TargetScan - Online software provided by MIT for prediction of microRNA targets. Provides research data and online software for microRNA target identification and analysis.
• Transcriptional Gene Silencing - Mechanisms of TGS by Kevin Morris laboratory. Includes description of HIV research performed using lentiviral vector gene therapy and RNAi mediated gene silencing.
• A TV Show on RNAi by PBS - NOVA scienceNOW TV program describes RNAi as a major breakthrough in gene therapy with enormous medical promise. Provides basic overview of RNAi technology, current therapeutic approaches, and interview with the experts in the field. Includes 15-minutes TV broadcast segment on RNAi.
• Wikipedia Article on RNAi - Online article describing the basics of RNA Interference (RNAi) mechanism.

• Small RNAs: Delivering the future - Article by journal Nature about development of RNAi therapeutics. (December 12, 2007)
• InFocus RNAi Web Broadcast by Bio.com - Review of RNAi advances, technologies and applications. Bio.com provides an online RNAi technology-focused webcast, experts in the field discuss new insights into the regulation of gene expression by RNAi. (November 16, 2006)
• MicroRNA in Cancer - Review of microRNA role in cancer by Nature journal. Provides full-length research papers and reviews. (June 9, 2005)
• RNAi Therapeutics: How Likely, How Soon? - Review article from PLoS Biology journal. Describes mechanism of RNA Interference, potential applications towards therapeutics, and current problems associated with delivery. (January 20, 2004)
• Induction of an interferon response by RNAi vectors in mammalian cells - Article from journal Nature Genetics about potential complications of use of RNAi vector-based technology for therapeutics. (June 8, 2003)

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