East Central Illinois consists of the following Illinois counties: Champaign, Ford, Iroquois, Vermilion, Edgar, Douglas, Coles, Clark, Cumberland, Piatt and Moultrie. The largest cities in the region are Champaign-Urbana, Charleston-Mattoon, and Danville. The largest universities in the region are the University of Illinois in Champaign-Urbana and Eastern Illinois University in Charleston.

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