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Articles and Research
Health: Mental Health: Disorders: Mood: Articles and Research
Adult Depression: Effective Treatments
- Documented treatments for depressed adults: medications, psychotherapy, ECT, well-studied alternative treatments. October 2007 By Glenn Brynes PhD MD
Algorithm for the Pharmacotherapy of Depression
- A detailed algorithm for treating depression in adults. It includes major depression, dysthymic depression, delusional depression and bipolar illness in a depressed phase. By David N. Osser, M.D. (January 24, 2003)
Antepartum Depression Treatment
- Treatment successes in an open trial of light therapy for pregnant women, published in the American Journal of Psychiatry.
Cancer and Emotions: Is it Normal to be Depressed?
- The main categories of psychological distress for patients with cancer include adjustment problems; depression; and anxiety. By Michelle B. Riba, M.D., M.S.
Depressed? Take a Hike
- Brisk walking can boost the mood of depressed patients, comparable to those of an antidepressant for mild to moderate depression, researchers at Duke University found.
Depression drugs may lead to apathy in the elderly
- Dr. Wongpakaran and others from the University of Toronto compared 160 treated with SSRIs to 224 treated with a non-SSRI antidepressant.
Depression in Women: Diagnostic and Treatment Considerations - American Family Physician
- Paper that discusses diagnosis, treatment and the reproductive life cycle. Subhash C. Bhatia, M.D. and Shashi K. Bhatia, M.D. (July 1,1999)
Email-based promotion of self-help for subthreshold depression
- PubMed citation for a study that tested the effectiveness of an automated email-based campaign promoting self-help behaviors.
Gene Linked to Alcoholism and Depression
- CHRM2 gene, on chromosome 7; strongly associated both with alcoholism and depression. From Washington University School of Medicine. (September 16, 2004)
Genetics of Recurrent Early-Onset Depression
- A research study used to identify genes that place individuals at risk for developing Major Depression and related disorders.
How we learned to stop having fun
- Barbara Ehrenreich traces depression from its 17th century beginnings of a concern with self--"the new individualism", and Calvinism. An edited extract from "Dancing in the Streets: A History of Collective Joy." The Guardian, (April 2, 2007)
Is Our Worship of Consumerism and Technology Making Us Depressed?
- Review and excerpt from a book by Bruce E. Levine that delves into the roots of depression and links our increasingly consumer-based culture and standard-practice psychiatric treatments to worsening depression. (November 25, 2007)
LiveScience: Good News About the Blues: Scientists Discover Gene Therapy for Depression
- Scientists have discovered a gene that makes mice happy, a finding that suggests another avenue of drugs for improving depression in humans. (December 28, 2006)
The Malaise Theory of Depression
- Paper proposing that major depressive disorder is inappropriate 'sickness behavior' generated by abnormalities in cytokines, and that antidepressants exert their specifically beneficial effects through analgesic action on the core dysphoric emotion of malaise. by Bruce G Charlton MD
Monash University - The DARE Project
- Participate in or refer to a depression research study at Monash University Melbourne, in Mindfulness-based cognitive therapy (MBCT) to prevent depressive relapse.
PubMed: Antidepressant efficacy of Sudarshan Kriya Yoga (SKY) in melancholia
- a randomized comparison with electroconvulsive therapy (ECT) and imipramine. The recommendation is though inferior to ECT, SKY can be a potential alternative to drugs in melancholia as a first line treatment.
PubMed: Crocus sativus L. in the treatment of mild to moderate depression
- Abstract on a double-blind, randomized and placebo-controlled trial in which Crocus sativus produced a significantly better outcome on the Hamilton depression rating scale than the placebo. (2005 John Wiley & Sons, Ltd)
PubMed: Enhancement of the antidepressant action of fluoxetine by folic acid
- Abstract of a study found that folic acid greatly improves the antidepressant action of fluoxetine and probably other antidepressants. (Nov. 2000)
PubMed: Potential treatment for subthreshold and mild depression
- Abstract of a comparison of St. John's wort extracts and fluoxetine suggests thta St. John's wort might be a treatment option to reduce symptoms in patients not suffering from full-blown depressive disorder. (March, April 2000)
PubMed: Treatment of men with major depression
- A comparison of sequential cohorts treated with either cognitive-behavioral therapy or newer generation antidepressants found that depressed men treated with pharmacotherapy had significantly greater improvements.
- A view of depression from the perspective of "voicelessness" theory. by Richard A. Grossman, Ph.D.
The Economist: Something in the way he moves
- Yoshiharu Yamamoto of the University of Tokyo and colleagues measured how often subjects changed rate of movement and found that depressed people experience longer resting periods more frequently and shorter ones less frequently than healthy people do. Sept. 27, 2007. (September 27, 2007)
NPR : Clues to Depression Sought in Brain's Wiring
- Michele Trudeau reports on brain imaging technologies and genetic detective work that reveal what can cause depression and how best to treat it. [8:46 streaming audio broadcast] (August 24, 2004)
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