Scholarly research reports and papers by authoritative persons in the medical and/or scientific professions.

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Genetics of Recurrent Early-Onset Depression
A research study used to identify genes that place individuals at risk for developing Major Depression and related disorders.
The Malaise Theory of Depression
Paper proposing that major depressive disorder is inappropriate 'sickness behavior' generated by abnormalities in cytokines, and that antidepressants exert their specifically beneficial effects through analgesic action on the core dysphoric emotion of malaise. by Bruce G Charlton MD
PubMed: Crocus sativus L. in the treatment of mild to moderate depression
Abstract on a double-blind, randomized and placebo-controlled trial in which Crocus sativus produced a significantly better outcome on the Hamilton depression rating scale than the placebo. (2005 John Wiley & Sons, Ltd)
PubMed: Enhancement of the antidepressant action of fluoxetine by folic acid
Abstract of a study found that folic acid greatly improves the antidepressant action of fluoxetine and probably other antidepressants. (Nov. 2000)
PubMed: Potential treatment for subthreshold and mild depression
Abstract of a comparison of St. John's wort extracts and fluoxetine suggests thta St. John's wort might be a treatment option to reduce symptoms in patients not suffering from full-blown depressive disorder. (March, April 2000)
PubMed: Treatment of men with major depression
A comparison of sequential cohorts treated with either cognitive-behavioral therapy or newer generation antidepressants found that depressed men treated with pharmacotherapy had significantly greater improvements.
Voicelessness: Depression
A view of depression from the perspective of "voicelessness" theory. by Richard A. Grossman, Ph.D.
Is Our Worship of Consumerism and Technology Making Us Depressed?
Review and excerpt from a book by Bruce E. Levine that delves into the roots of depression and links our increasingly consumer-based culture and standard-practice psychiatric treatments to worsening depression. (November 25, 2007) (November 25, 2007)
Adult Depression: Effective Treatments
Documented treatments for depressed adults: medications, psychotherapy, ECT, well-studied alternative treatments. By Glenn Brynes PhD MD (October 01, 2007)
The Economist: Something in the way he moves
Yoshiharu Yamamoto of the University of Tokyo and colleagues measured how often subjects changed rate of movement and found that depressed people experience longer resting periods more frequently and shorter ones less frequently than healthy people do. Sept. 27, 2007. (September 27, 2007)
TheGuardian: How we learned to stop having fun
Barbara Ehrenreich traces depression from its 17th century beginnings of a concern with self--"the new individualism", and Calvinism. An edited extract from "Dancing in the Streets: A History of Collective Joy." (April 02, 2007)
LiveScience: Good News About the Blues: Scientists Discover Gene Therapy for Depression
Scientists have discovered a gene that makes mice happy, a finding that suggests another avenue of drugs for improving depression in humans. (December 28, 2006) (December 28, 2006)
Gene Linked to Alcoholism and Depression
CHRM2 gene, on chromosome 7; strongly associated both with alcoholism and depression. From Washington University School of Medicine. (September 16, 2004) (September 16, 2004)
NPR : Clues to Depression Sought in Brain's Wiring
Michele Trudeau reports on brain imaging technologies and genetic detective work that reveal what can cause depression and how best to treat it. [8:46 streaming audio broadcast] (August 24, 2004)
Antepartum Depression Treatment
Treatment successes in an open trial of light therapy for pregnant women, published in the American Journal of Psychiatry. (April 01, 2002)
Depression in Women: Diagnostic and Treatment Considerations - American Family Physician
Paper that discusses diagnosis, treatment and the reproductive life cycle. Subhash C. Bhatia, M.D. and Shashi K. Bhatia, M.D. (July 1,1999) (July 01, 1999)
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